The Centers for Disease Control and Prevention say that if you are going to travel to Botswana, you should take the Malaria Vaccine, and other preventative medicines as long in advance as at least six weeks.  They also state that you should not go bare foot when you are in Botswana, for your own safety.  The CDC also recommends that you visit a doctor who specializes in Travel Medicine, so that you learn how to protect yourself from other illnesses and injuries, while you are away from home.  If you want even more information on how to prepare for this trip, please use this link and see what else the CDC suggests, for your safety and well being. http://wwwn.cdc.gov/travel/destinationBotswana.aspx